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Started by FrankieTeardrop on Nov 19, 2020 7:28:58 PM
Dupixent

Dupixent is a monoclonal antibody treatment for eczema. I know someone who has been using it and it had changed their life. I’m sick of having horrible skin and would like to try it myself. Has anyone else tried it, or know how to persuade the NHS to prescribe it?

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thisonehasalittlehat - 19 Nov 2020 20:22:12 (#1 of 19)

Daorklis

helbel - 19 Nov 2020 20:24:52 (#2 of 19)

I can’t comment on this directly or how to persuade the NHS, but my colleague has a monoclonal antibody treatment for his severe asthma. Again life changing. Go for it if you can.

Tenesmus - 19 Nov 2020 20:36:13 (#3 of 19)

https://bnf.nice.org.uk/medicinal-forms/dupilumab.html

Have you asked your GP or consultant?

FrankieTeardrop - 19 Nov 2020 23:14:22 (#4 of 19)

Just spoke to them today to get a dermatology appointment.

FrankieTeardrop - 20 Nov 2020 12:12:58 (#5 of 19)

I can’t comment on this directly or how to persuade the NHS, but my colleague has a monoclonal antibody treatment for his severe asthma. Again life changing. Go for it if you can.


Ah good for them - was it the same stuff, or a different one? I hope it is the same, it could clear up my asthma at the same time.

I've noted the NHS guidance is to use Dupixent when other treatments have failed - other treatments being immunosuppressants. I don't want to take those during a pandemic, though

helbel - 20 Nov 2020 12:26:37 (#6 of 19)

Sorry I don’t know the name of it. I know my colleague was on max steroid doses and every time they tried to reduce his steroid dose it didn’t go well. So he was a prime candidate for the treatment as his asthma was uncontrolled by normal options.

FrankieTeardrop - 20 Nov 2020 12:34:09 (#7 of 19)

That's the same with steroids on my skin - I can't stop using them.

binturong - 26 Nov 2020 08:42:33 (#8 of 19)

immunosuppressants. I don't want to take those during a pandemic, though

Some treatments ate curently being used in non-standard orders of preference for exactly this reason - for example my brother-out-law is on immunotherapy rather than chemo for his cancer because it leaves his immune system in better shape. Not sure whether it's relevant in your case, but certainly worth asking your GP. I'll have a rummage in the Covid guidance to see if I can find anything.

FrankieTeardrop - 26 Nov 2020 09:33:53 (#9 of 19)

Thanks Binturong.

I've arranged and appointment with a dermatologist - might take weeks before I can see them. I'm expecting a whole load of hoops to jump through, the NICE guidance says Dupixent is prescribed only where other treatments have failed.

binturong - 27 Nov 2020 13:06:02 (#10 of 19)

Sorry - can't find anything on treatment variation for eczema during the pandemic. There's some for asthma, and for general autoimmune conditions, but it's mainly about methods of administering treatment for people already on biologics rather than on switching people onto them in the first place.

FrankieTeardrop - 23 Mar 2022 09:42:23 (#11 of 19)

I've jumped through the immunosuppressant hoops, been rendered ill by methotrexate, and finally been prescribed the good stuff.

I had my initial two doses last week and just injected myself this morning. About ten minutes after injection I noticed a "calm" feeling, like when you have antihistamines and an allergy recedes.

I've been using steroid creams but on a reducing dose, ran out on Monday. Skin was a bit sore this morning, but the dose of Dupilimab seems to have improved that.

FrankieTeardrop - 23 Mar 2022 09:42:42 (#12 of 19)

Also noticed my nose feels less blocked and irritated.

tasselhoff - 23 Mar 2022 09:47:24 (#13 of 19)

Is Dupilimab the same as Dupixent?

mingmong - 23 Mar 2022 09:49:35 (#14 of 19)

Good luck Frankie

As a fellow sufferer, I will watching this thread with interest

JohnIlly - 23 Mar 2022 09:53:55 (#15 of 19)

Is Dupilimab the same as Dupixent?

The latter is the branded name.

tasselhoff - 23 Mar 2022 09:55:01 (#16 of 19)

Ta

FrankieTeardrop - 23 Mar 2022 09:56:01 (#17 of 19)

Is Dupilimab the same as Dupixent?


Yes, as John says, Dupixent developed/produce Dupilumab.

As a fellow sufferer, I will watching this thread with interest


Looking good so far, although I have one benchmark of success that hasn't been met yet...

mingmong - 23 Mar 2022 10:02:04 (#18 of 19)

good luck with that as well

helbel - 23 Mar 2022 10:28:58 (#19 of 19)

Very glad you’ve finally got to the good drugs! Fingers crossed they work well for you.

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